A Breath-activated, Precision Bolus Injection System for Human Inhalation-exposure and Drug Delivery Studies
نویسندگان
چکیده
paper presents the work carried out in developing a precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM into breath cycles by a process of dynamic breadth pattern analysis and statistical data relating to stored PM to achieve a highly controlled delivery within specified exposure times and intervals.
منابع مشابه
Development of a Bolus Injection System to Achieve Storage and Controlled Delivery of Nanoparticles to Human Lung
precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM into breath cycles by a process of dynamic breath pattern analysis and statistical data re...
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